Phenotypic Characteristics of Patients With Chronic Obstructive Pulmonary Disease After Stratification for the Short Physical Performance Battery Summary Score.

Autor:	Stoffels AAF; Department of Pulmonary Diseases, Dekkerswald Radboudumc, Nijmegen, the Netherlands; Department of Research and Development, CIRO, Horn, the Netherlands. Electronic address: anouk.stoffels@radboudumc.nl., De Brandt J; Reval Rehabilitation Research, Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium., Meys R; Department of Research and Development, CIRO, Horn, the Netherlands., van Hees HWH; Department of Pulmonary Diseases, Dekkerswald Radboudumc, Nijmegen, the Netherlands., Vaes AW; Department of Research and Development, CIRO, Horn, the Netherlands., Klijn P; Department of Pulmonology, Merem Pulmonary Rehabilitation Centre, Hilversum, the Netherlands; Department of Pulmonology, Amsterdam University Medical Centre, Amsterdam, the Netherlands., Burtin C; Reval Rehabilitation Research, Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium., Franssen FME; Department of Research and Development, CIRO, Horn, the Netherlands; Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, the Netherlands., van den Borst B; Department of Pulmonary Diseases, Dekkerswald Radboudumc, Nijmegen, the Netherlands., Sillen MJH; Department of Research and Development, CIRO, Horn, the Netherlands., Wouters EFM; Department of Research and Development, CIRO, Horn, the Netherlands., Janssen DJA; Department of Research and Development, CIRO, Horn, the Netherlands; Department of Health Services Research, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands., Spruit MA; Department of Research and Development, CIRO, Horn, the Netherlands; Reval Rehabilitation Research, Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium; Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, the Netherlands.
Jazyk:	angličtina
Zdroj:	Archives of physical medicine and rehabilitation [Arch Phys Med Rehabil] 2020 Nov; Vol. 101 (11), pp. 1887-1897. Date of Electronic Publication: 2020 Jun 01.
DOI:	10.1016/j.apmr.2020.05.011
Abstrakt:	Objective: To assess the phenotypic characteristics of patients with chronic obstructive pulmonary disease (COPD) after stratification for Short Physical Performance Battery (SPPB) summary scores and to determine phenotypic characteristics of the SPPB summary score at the start of pulmonary rehabilitation (PR). Design: Retrospective, cross-sectional. Setting: Baseline assessment for PR program. Participants: Patients with COPD (n=900; age 65±8y, 52% male, forced expiratory volume in the first second of expiration, 43% [interquartile range, 31%-62%] predicted). Interventions: Not applicable. Main Outcome Measures: Patients were stratified according to their SPPB summary scores into low-performance (LP), moderate-performance (MP), or high-performance (HP) groups. Furthermore, lung function, arterial blood gases, body composition, physical capacity, lower limb muscle strength and endurance, and symptoms of anxiety and depression were assessed. Results: Generally, physical capacity and muscle function were lower and scores for symptoms of anxiety and depression were higher in LP patients than MP and HP patients (all values, P<.01). However, 25% of HP patients with COPD scored high on symptoms of anxiety and/or depression (≥10 points), and HP patients still had on average an impaired physical capacity (median, 6-minute walk test [6MWT] distance of 69% predicted). Furthermore, age and 6MWT distance (m) were the only independent predictors in a multivariate regression model, explaining 29% of the variance in SPPB summary score. Conclusions: In COPD, LP patients have the worst physical and emotional functioning. However, HP patients can still exhibit physical and emotional impairments. Because the explained variance in SPPB summary score is low, SPPB should not be considered as a test to discriminate between patients with COPD with a low or preserved physical capacity and emotional status. (Copyright © 2020 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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