Infertility and assisted reproductive technology outcomes in Afro-Caribbean women.

Autor: Wiltshire A; Department of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, Atlanta, GA, 30310, USA. ashleyfimrc@gmail.com., Ghidei L; Department of Obstetrics and Gynecology, Brown University Alpert Medical School, and Women & Infants Hospital, 101 Dudley Street, Providence, RI, 02905, USA., Brayboy LM; Division of Reproductive Endocrinology and Infertility, Women & Infants Hospital, 101 Dudley Fl 1, Providence, RI, 02905, USA.
Jazyk: angličtina
Zdroj: Journal of assisted reproduction and genetics [J Assist Reprod Genet] 2020 Jul; Vol. 37 (7), pp. 1553-1561. Date of Electronic Publication: 2020 May 27.
DOI: 10.1007/s10815-020-01826-2
Abstrakt: Objective: To assess the causes of infertility and artificial reproductive technology (ART) outcomes in women of African descent living in the Caribbean and Bermuda.
Design: Cross-sectional study composed of a questionnaire administered to providers who care for women undergoing ART in the Caribbean and Bermuda.
Material and Methods: A questionnaire from the Deerfield Institute was adapted to meet the aims of our study with their permission. Eight infertility clinics in the Caribbean and Bermuda were identified. The primary physician at each site was contacted via email and invited to participate in the study. Questionnaires were completed via interview or electronically. Responses were collected in a REDCap database for statistical analysis.
Results: There were five respondents from Barbados, Bermuda (× 2), Puerto Rico, and the Bahamas. The most commonly reported etiologies of infertility among Afro-Caribbean patients were female-male factor and uterine factor. In vitro fertilization (IVF) combined with intracytoplasmic sperm injection (ICSI) is performed more often than conventional IVF. The cumulative live birth rates (LBR) after ART for those ages ≤ 34, 35-37, 38-42, and > 42 were 52%, 40%, 22%, and 12%, respectively. The cumulative live birth rate was 31.5% for total patients. The factors reported to be most important in hindering patients from cycling were coping emotionally with poor ovarian response and cost. The biggest restraints to infertility care were costs and a lack of local IVF centers on all islands.
Conclusion: Afro-Caribbean women receiving infertility care in the Caribbean may have better ART outcomes compared to African-American women in the United States (US).
Databáze: MEDLINE
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