[Clinical features of coronavirus disease 2019 in children aged <18 years in Jiangxi, China: an analysis of 23 cases].
| Autor: | Wu HP; Department of Pediatrics, Jiangxi Provincial Children's Hospital/Children's Hospital, Nanchang University, Nanchang 330006, China. jx-cq@163.com., Li BF, Chen X, Hu HZ, Jiang SA, Cheng H, Hu XH, Tang JX, Zhong FC, Zeng LW, Yu W, Yuan Y, Wu XF, Li YP, Zheng ZL, Pan TB, Wu ZX, Yuan JF, Chen Q |
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| Jazyk: | čínština |
| Zdroj: | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics [Zhongguo Dang Dai Er Ke Za Zhi] 2020 May; Vol. 22 (5), pp. 419-424. |
| Abstrakt: | Objective: To study the clinical features of coronavirus disease 2019 (COVID-19) in children aged <18 years. Methods: A retrospective analysis was performed from the medical data of 23 children, aged from 3 months to 17 years and 8 months, who were diagnosed with COVID-19 in Jiangxi, China from January 21 to February 29, 2020. Results: Of the 23 children with COVID-19, 17 had family aggregation. Three children (13%) had asymptomatic infection, 6 (26%) had mild type, and 14 (61%) had common type. Among these 23 children, 16 (70%) had fever, 11 (48%) had cough, 8 (35%) had fever and cough, and 8 (35%) had wet rales in the lungs. The period from disease onset or the first nucleic acid-positive detection of SARS-CoV-2 to the virus nucleic acid negative conversion was 6-24 days (median 12 days). Of the 23 children, 3 had a reduction in total leukocyte count, 2 had a reduction in lymphocytes, 2 had an increase in C-reactive protein, and 2 had an increase in D-dimer. Abnormal pulmonary CT findings were observed in 12 children, among whom 9 had patchy ground-glass opacities in both lungs. All 23 children received antiviral therapy and were recovered. Conclusions: COVID-19 in children aged <18 years often occurs with family aggregation, with no specific clinical manifestation and laboratory examination results. Most of these children have mild symptoms and a good prognosis. Epidemiological history is of particular importance in the diagnosis of COVID-19 in children aged <18 years. |
| Databáze: | MEDLINE |
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