Volume-assured pressure support mode plus pirfenidone as resuscitation therapy in patients with exacerbation of idiopathic pulmonary fibrosis.

Autor: Briones Claudett KH; Universidad de Guayaquil, Facultad de Ciencias Médicas, Guayaquil, Ecuador. killenbrio@hotmail.com.; Centro Fisiológico-Respiratorio Briones-Claudett, Guayaquil, Ecuador. killenbrio@hotmail.com.; Intensive Care Unit, Ecuadorian Institute of Social Security, Babahoyo, Ecuador, Juan Anoleto, Babahoyo, Ecuador. killenbrio@hotmail.com., Briones Claudett MH; Centro Fisiológico-Respiratorio Briones-Claudett, Guayaquil, Ecuador.; Intensive Care Unit, Ecuadorian Institute of Social Security, Babahoyo, Ecuador, Juan Anoleto, Babahoyo, Ecuador., Vargas Domenica E; Universidad de Guayaquil, Facultad de Ciencias Médicas, Guayaquil, Ecuador.; Centro Fisiológico-Respiratorio Briones-Claudett, Guayaquil, Ecuador., Rodriguez Garcia S; Universidad de Guayaquil, Facultad de Ciencias Médicas, Guayaquil, Ecuador.; Centro Fisiológico-Respiratorio Briones-Claudett, Guayaquil, Ecuador., Benites Solis J; OMNI Hospital, Abel Castillo Romero y Av. Juan Tanca Marengo, Guayaquil, Ecuador., Andrade Cabrera C; Intensive Care Unit, Ecuadorian Institute of Social Security, Babahoyo, Ecuador, Juan Anoleto, Babahoyo, Ecuador., Grunauer Andrade M; Universidad San Francisco de Quito, Quito, Ecuador.; School of Medicine, Quito, Ecuado.
Jazyk: angličtina
Zdroj: Advances in respiratory medicine [Adv Respir Med] 2020; Vol. 88 (2), pp. 147-152.
DOI: 10.5603/ARM.2020.0077
Abstrakt: Introduction: Treatment among advanced stage idiopathic pulmonary fibrosis is quite challenging, especially considering that no major evidence has been released about it. This case report demonstrates and discusses the benefit of non-invasive mechanical ventilation in volume-assured pressure support (AVAPS) mode plus pirfenidone based on the relief of apatient'ssymptoms in combination with high-resolution computed tomography (HRCT) evidence.
Material and Methods: An 83-year-old female patient with multiple hospital admissions within a six-month period initially presented with cardiac symptoms which were later attributed to apossible exacerbation of her primary diagnosis, idiopathic pulmonary fibrosis.
Conclusion: The addition of non-invasive mechanical ventilation in AVAPS mode plus pirfenidone can improve the survival rates even in patients with current exacerbations of acute respiratory failure due to idiopathic pulmonary fibrosis.
Databáze: MEDLINE