Co-activation of rhythms during alpha band oscillations as an interictal biomarker of exploding head syndrome.

Autor: Fotis Sakellariou D; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Basic and Clinical Neuroscience, IoPPN, King's College London, London, UK., Nesbitt AD; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Basic and Clinical Neuroscience, IoPPN, King's College London, London, UK.; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Headache Group, Department of Clinical Neurosciences, King's College Hospital NHS Foundation Trust, London, UK., Higgins S; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Beniczky S; Danish Epilepsy Centre, Dianalund, Denmark.; Aarhus University Hospital, Aarhus, Denmark., Rosenzweig J; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Department of Engineering, King's College London, UK., Drakatos P; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Gildeh N; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Murphy PB; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Kent B; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Williams AJ; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Kryger M; Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, Connecticut, USA., Goadsby PJ; Basic and Clinical Neuroscience, IoPPN, King's College London, London, UK.; Headache Group, Department of Clinical Neurosciences, King's College Hospital NHS Foundation Trust, London, UK.; NIHR-Wellcome Trust Clinical Research Facility, SLaM Biomedical Research Centre, King's College London, London, UK., Leschziner GD; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Basic and Clinical Neuroscience, IoPPN, King's College London, London, UK.; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Rosenzweig I; Sleep and Brain Plasticity Centre, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; Sleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Danish Epilepsy Centre, Dianalund, Denmark.; Aarhus University Hospital, Aarhus, Denmark.
Jazyk: angličtina
Zdroj: Cephalalgia : an international journal of headache [Cephalalgia] 2020 Aug; Vol. 40 (9), pp. 949-958. Date of Electronic Publication: 2020 Apr 10.
DOI: 10.1177/0333102420902705
Abstrakt: Background: Exploding head syndrome is a rarely reported benign sensory parasomnia that may nonetheless have significant impact on patients' quality of life and their perceived well-being. To date, the mechanisms underlying attacks, characterised by a painless perception of abrupt, loud noises at transitional sleep-wake or wake-sleep states, are by and large unclear.
Methods and Results: In order to address the current gap in the knowledge of potential underlying pathophysiology, a retrospective case-control study of polysomnographic recordings of patients presenting to a tertiary sleep disorders clinic with exploding head syndrome was conducted. Interictal (non-attack associated) electroencephalographic biomarkers were investigated by performing macrostructural and event-related dynamic spectral analyses of the whole-night EEG. In patients with exploding head syndrome, additional oscillatory activity was recorded during wakefulness and at sleep/wake periods. This activity differed in its frequency, topography and source from the alpha rhythm that it accompanied.
Conclusion: Based on these preliminary findings, we hypothesise that at times of sleep-wake transition in patients with exploding head syndrome, aberrant attentional processing may lead to amplification and modulation of external sensory stimuli.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje