| Autor: |
Lin F; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Wang Z; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Chen J; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada. hongbo.zeng@ualberta.ca., Lu B; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Tang L; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Chen X; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Lin C; Fujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou 350108, China., Huang B; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn., Zeng H; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada. hongbo.zeng@ualberta.ca., Chen Y; College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China. fjaucyd@163.com bhuang@fafu.edu.cn. |
| Abstrakt: |
Developing physical hydrogels with advanced mechanical performance and multi-functionalities as alterative materials for load-bearing soft tissues remains a great challenge. Biological protein-based materials generally exhibit superior strength and toughness owing to their hierarchical structures via hydrogen-bonding assembly. Inspired by natural biological protein materials, tannic acid (TA) is exploited as a molecular coupling bridge between cellulose nanocrystals (CNCs) and poly(vinyl alcohol) (PVA) chains for the fabrication of a bio-based advanced physical hydrogel via strong multiple H-bonds. When exposed to mechanical stress, the sacrificial H-bonds can dissipate energy effectively on the molecular scale via dynamic rupture and reformation, endowing these biomimetic hydrogels with remarkable toughness, ultrahigh strength, large elongation, and good self-recoverability, which are much superior to those of most hydrogen bond-based hydrogels. Moreover, the characteristics of TA endow these biomimetic hydrogels with versatile adhesiveness and good antibacterial properties. This work presents an innovative biomimetic strategy for robust biocompatible hydrogels with superior mechanical strength and functionalities, which holds great promise for applications in tissue engineering and biomedical fields. |
