Management and outcomes following emergency surgery for traumatic brain injury - A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study).

Autor:	Clark D; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University Teaching Hospital, Lusaka, Zambia., Joannides A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Ibrahim Abdallah O; Sohag University Hospitals, Sohag, Egypt., Olufemi Adeleye A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University College Hospital Ibadan, Ibadan, Oyo, Nigeria., Hafid Bajamal A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Dr Soetomo Hospital, Surabaya, Jawa Timur, Indonesia., Bashford T; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University of Cambridge, Cambridge, Cambridgeshire, United Kingdom., Bhebhe A; University Teaching Hospital, Lusaka, Zambia., Biluts H; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Neurosurgery Unit, Surgery Department, Addis Ababa University, College of Health Sciences, Addis Ababa, Oromia, Ethiopia., Budohoska N; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Budohoski K; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Cherian I; Nobel Medical College Teaching Hospital P Ltd, Biratnagar, Morang, Nepal., Marklund N; Lund University, Skane University Hospital, Lund, Sweden., Fernandez Mendez R; University of Cambridge, Cambridge, Cambridgeshire, United Kingdom., Figaji T; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University of Cape Town, Rondebosch, Western Cape, South Africa., Kumar Gupta D; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; All India Institute of Medical Sciences, New Delhi, Delhi, India., Iaccarino C; University Hospital of Parma, Parma, Emilia-Romagna, Italy., Ilunga A; University Teaching Hospital, Lusaka, Zambia., Joseph M; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Christian Medical College Vellore Association, Vellore, Tamil Nadu, India., Khan T; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; North West General Hospital & Research Center, Peshawar, Khyber Pakhtunkhwa, Pakistan., Laeke T; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Neurosurgery Unit, Surgery Department, Addis Ababa University, College of Health Sciences, Addis Ababa, Oromia, Ethiopia., Waran V; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University of Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan, Malaysia., Park K; Harvard Medical School, Boston, MA, USA., Rosseau G; George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Rubiano A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Universidad El Bosque, Department of Neurosurgery, Bogota, Colombia., Saleh Y; University of Oxford, Oxford, Oxfordshire, United Kingdom., Shabani HK; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Muhimbili Orthopaedic Institute and Muhimbili University College of Allied Health Sciences, Dar es Salaam, Tanzania., Smith B; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Sichizya K; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; University Teaching Hospital, Lusaka, Zambia., Tewari M; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Post Graduate Institute of Medical Education and Research Chandigarh, Chandigarh, India., Tirsit A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Tikur Anbessa Specialized Hospital, Addis Ababa University, Addis Ababa, Oromia, Ethiopia., Thu M; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Yangon General Hospital, Yangon, Yangon Region, Myanmar., Tripathi M; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; Post Graduate Institute of Medical Education and Research Chandigarh, Chandigarh, India., Trivedi R; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Villar S; MRC Biostatistics Unit, Cambridge, Cambridgeshire, UK., Devi Bhagavatula I; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.; National Institute of Mental Health & Neuro Science, Bangalore, India., Servadei F; Humanitas University and Research Hospital, Department of Neurosurgery, Milan, Italy., Menon D; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Kolias A; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Hutchinson P; National Institute of Health Research Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.
Jazyk:	angličtina
Zdroj:	International journal of surgery protocols [Int J Surg Protoc] 2020 Feb 28; Vol. 20, pp. 1-7. Date of Electronic Publication: 2020 Feb 28 (Print Publication: 2020).
DOI:	10.1016/j.isjp.2020.02.001
Abstrakt:	Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and Analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and Dissemination: This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2020 The Authors.)
Databáze:	MEDLINE
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