A Four-Year Hospital-Based Retrospective Study of the Predictors of Tuberculosis in People Living with HIV and Receiving Care at Bamenda Regional Hospital, Cameroon.

Autor:	Anye CS; Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.; Cameroon Baptist Convention Health Services, Yaounde, Cameroon., Nkfusai CN; Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.; Cameroon Baptist Convention Health Services, Yaounde, Cameroon., Yankam BM; Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon., Wirsiy FS; Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Tsoka-Gwegweni JM; Office of the Dean, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa., Cumber SN; Office of the Dean, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.; Section for Epidemiology and Social Medicine, Department of Public Health, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Box 414, SE - 405 Gothenburg, Sweden.; School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria Private Bag X323, Gezina, Pretoria, 0001, Pretoria, South Africa.
Jazyk:	angličtina
Zdroj:	International journal of MCH and AIDS [Int J MCH AIDS] 2020; Vol. 9 (2), pp. 167-172. Date of Electronic Publication: 2020 Feb 18.
DOI:	10.21106/ijma.299
Abstrakt:	Background: Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) co-infections place immense burdens on healthcare systems with particularly diagnostic and therapeutic challenges. TB is high among opportunistic diseases and the most leading cause of death among patients with HIV/AIDS. HIV infection is the most-known risk factor for Mycobacterium tuberculosis infection and progression to active disease, which increases the risk of latent TB reactivation by 20-fold. We present a four-year descriptive analysis of TB in people living with HIV in the Bamenda Regional Hospital (BRH) from 2012-2016. Methods: This was a hospital-based descriptive chart review. We conducted manual reviews of medical records of HIV/TB co-infected patients from June 2017-July 2017 at BRH's AIDS Treatment Centre, North West region of Cameroon. Socio-demographic and clinical characteristics of cases were captured using a pre-tested data collection sheet and analyzed with Statistical Package for Social Sciences (SPSS) software, version 25. Results: Out of the 1078 HIV patients, 36.5% (393) of them were diagnosed with TB; 75% (808) of the People living with HIV (PLWHIV) were active; among the remaining 25%, 10.2% were bedridden, 13.0% were jobless, and 1.8% were retired. The greater proportion of the participants were females 65.5% (705). Conclusion and Global Health Implications: The baseline anemia, smoking tobacco, drinking alcohol, detectable (≥50copies/mL), CD4 count ≤ 200cells/µl and gender of the PLWHIV were associated with the incidence of TB. We recommend early diagnosis and treatment of anemia, modification of patient's lifestyle, and strengthening of immunization programs to reduce the risk of TB occurrence among HIV-infected people. (Copyright © 2020 Anye et al.)
Databáze:	MEDLINE
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