Primary Cutaneous Aspergillosis in Immunocompetent Adults: Three Cases and a Review of the Literature.
| Autor: | Avkan-Oğuz V; Infectious Diseases and Clinical Microbiology, Dokuz Eylul University, School of Medicine, Izmir, TUR., Çelik M; Infectious Diseases and Clinical Microbiology, Dokuz Eylul University, School of Medicine, Izmir, TUR., Satoglu IS; Orthopaedics and Traumatology, Dokuz Eylul University Faculty of Medicine, Izmir, TUR., Ergon MC; Medical Microbiology, Dokuz Eylul University, School of Medicine, İzmir, TUR., Açan AE; Orthopaedics and Traumatology, Balıkesir University, Medical Faculty, Balıkesir, TUR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2020 Jan 08; Vol. 12 (1), pp. e6600. Date of Electronic Publication: 2020 Jan 08. |
| DOI: | 10.7759/cureus.6600 |
| Abstrakt: | Primary cutaneous aspergillosis (PCA) can rarely affect immunocompetent people. There is limited knowledge about the prevalence, diagnosis and management of the disease because there are only case reports or small case series in the literature. For this reason, the diagnosis and treatment of three immunocompetent adult patients diagnosed with PCA were discussed by reviewing the literature. In the current report, in addition to treatment with voriconazole for 8-12 weeks we performed repeated surgical debridement for the treatment of these cases. After two negative tissue cultures, the wounds were either successfully closed primarily or reconstructed using a skin graft. Management of PCA cases will become easier as more reports and further studies of PCA contribute to our shared knowledge. Currently, the most appropriate management approach is to make individualized treatment decisions according to the patients' clinical features and treatment response which includes several surgical debridement as well as antifungal therapy. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Avkan-Oğuz et al.) |
| Databáze: | MEDLINE |
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