Comparative study on the efficacy of non-steroidal, steroid and non-use of anti-inflammatory in the treatment of acute epidemic conjunctivitis.

Autor:	Santiago LA; Master in Surgery, and Physician, Hospital de Olhos Leiria de Andrade, Fortaleza-CE, Brazil. Acquisition of data, technical procedures, manuscript writing., Silva JMRD; Fellow Master degree, Pharmacology Department, Universidade Federal do Ceará (UFC), Fortaleza-CE, Brazil. Statistical analysis, analysis and interpretation of data, technical procedures., Azevedo OGR; Pos Doc, Postgraduate Program, Department of Surgery, UFC, Fortaleza-CE, Brazil. Manuscript preparation and writing, critical revision., Vasconcelos PRL; PhD, Full Professor, Coordinator, Postgraduate Program in Surgery, Department of Surgery, UFC, Fortaleza-CE, Brazil. Intellectual and scientific content of the study, critical revision, final approval.
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2020 Feb 07; Vol. 34 (12), pp. e201901206. Date of Electronic Publication: 2020 Feb 07 (Print Publication: 2020).
DOI:	10.1590/s0102-865020190120000006
Abstrakt:	Purpose: To evaluate the effects of prednisolone against sodium diclofenac both with ciprofloxacin compared to artificial tears on the symptoms and signs of acute viral conjunctivitis. Methods: Study included 37 patients diagnosed with acute conjunctivitis and distributed by three groups: A (1% prednisolone acetate + ciprofloxacin (0.3%); B (Sodium diclofenac (0.1%) + ciprofloxacin (0.3%) and C (artificial tears + ciprofloxacin (0.3%). Patients received medication 6/6 hours daily. Signs and symptoms (e.g. lacrimation, burning, photophobia, etc.) were scored at baseline and on the first, third, fifth and seventh days and in the end of treatment using a standardized questionnaire and slit lamp anterior segment examination. Results: All three groups demonstrated an improvement in the signs and symptoms of conjunctivitis in their follow-up visits. There was no significant difference in symptom and sign scores between Group A and B and B and C in the study visits ( p >0.05). However, the comparison between groups A and C showed a clinical trend (p=0.05) on third evaluation suggesting better clinical action using the corticosteroids. Conclusion: The prednisolone acetate was not superior to the use of sodium diclofenac or artificial tears in relieving the signs and symptoms of viral conjunctivitis.
Databáze:	MEDLINE
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