Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects.

Autor:	Cunha JLS; University of Campinas (UNICAMP), Piracicaba Dental School, Department of Oral Diagnosis. Piracicaba, SP, Brazil., Ramos MACDC; Tiradentes University, Department of Dentistry. Aracaju, SE, Brazil., Regis DM; Tiradentes University, Department of Dentistry. Aracaju, SE, Brazil., Sanchéz-Romero C; University of Campinas (UNICAMP), Piracicaba Dental School, Department of Oral Diagnosis. Piracicaba, SP, Brazil., de Andrade ME; Tiradentes University, Institute of Technology and Research, Laboratory of Morphology and Experimental Pathology. Aracaju, SE, Brazil., Bezerra BT; Tiradentes University, Department of Dentistry. Aracaju, SE, Brazil., de Albuquerque-Júnior RLC; Tiradentes University, Institute of Technology and Research, Laboratory of Morphology and Experimental Pathology. Aracaju, SE, Brazil.
Jazyk:	angličtina
Zdroj:	Autopsy & case reports [Autops Case Rep] 2020 Jan 21; Vol. 10 (1), pp. e2020140. Date of Electronic Publication: 2020 Jan 21 (Print Publication: 2020).
DOI:	10.4322/acr.2020.140
Abstrakt:	Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition. Competing Interests: Conflict of interest: None (Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2020.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu