[Short-term results of pancreatoduodenectomy in patients over 70 years old].

Autor: Shatveryan GA; Petrovsky National Research Centre of Surgery, Moscow, Russia., Chardarov NK; Petrovsky National Research Centre of Surgery, Moscow, Russia., Nikoda VV; Petrovsky National Research Centre of Surgery, Moscow, Russia., Bagmet NN; Petrovsky National Research Centre of Surgery, Moscow, Russia., Tadzhibova IM; Petrovsky National Research Centre of Surgery, Moscow, Russia., Lishova EA; Petrovsky National Research Centre of Surgery, Moscow, Russia., Ratnikova NP; Petrovsky National Research Centre of Surgery, Moscow, Russia., Karagyozyan GA; Petrovsky National Research Centre of Surgery, Moscow, Russia.
Jazyk: English; Russian
Zdroj: Khirurgiia [Khirurgiia (Mosk)] 2020 (1), pp. 25-32.
DOI: 10.17116/hirurgia202001125
Abstrakt: Objective: To analyze the immediate results of PDE in patients younger and older 70 years.
Material and Methods: The study included patients who underwent PDE for various indications from March 2010 to February 2019. All patients are divided into 2 groups: <70 years old and ≥70 years old. Primary endpoints were postoperative mortality and complication rate.
Results: There were 110 procedures within 9 years. There were 93 patients aged <70 years (group 1) and 17 patients aged ≥70 years (group 2). ASA (American Society of Anesthesiologists) and PMP scores (Preoperative Mortality Predictor) were higher in group 2: 3 (2-3) vs 2 (1-3) (p=0,002) and 12 (6-15) vs 6.5 (5-15) (p<0.001), respectively. Mortality rate was higher in group 2 (11.7% vs. 3.2%) without statistical significance (p=0.16). Overall morbidity (72% vs 76%; p=1.0), incidence of major complications grade ≥IIIa (29% vs 29%), delayed gastric emptying B/C (17.2% vs 17.6%), pancreatic fistula grade B/C (23.6% vs 35.3%, p=0.3), biliary fistula grade B/C (7.5% vs 11.8%; p=0.62), postoperative hospital-stay [22 (8-165) days vs 23 (9-71) days; p=0.92] were comparable in both groups.
Conclusion: Short-term results of PDE in patients aged <70 and ≥70 years are comparable despite higher ASA and PMP scores in the group 2. General status and concomitant diseases should be considered during selection of patients with resectable tumors for PDE. Age per se is not a contraindication for surgery.
Databáze: MEDLINE