Efficacy of a propolis solution for cleaning complete dentures.

Autor:	de Souza RF; Faculty of Dentistry, McGill University, Montreal, QC, Canada., Silva-Lovato CH; Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil, chl@forp.usp.br., de Arruda CN; Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Regis RR; School of Dentistry, Federal University of Ceará, Fortaleza, CE, Brazil., Zanini AP; School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Longo DL; School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Peracini A; School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., de Andrade IM; School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Watanabe E; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Paranhos HF; Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Jazyk:	angličtina
Zdroj:	American journal of dentistry [Am J Dent] 2019 Dec; Vol. 32 (6), pp. 306-310.
Abstrakt:	Purpose: The efficacy of a propolis solution against denture biofilm was evaluated by means of an in vitro assessment and a cross-over randomized clinical trial. Methods: Acrylic resin specimens were contaminated by Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Candida albicans, Candida glabrata, Candida parapsilosis, immersed in a (A) propolis solution, (B) saline or (C) alkaline peroxide, applied onto Petri plates with culture medium and after incubation the number of colonies was counted. For the clinical trial, 30 complete denture wearers were randomly assigned to groups (A) propolis solution, and (B) saline, following one of the sequences (I)A/B or (II) B/A. After each intervention, biofilm was quantified by means of digital photos taken from the intaglio surface and a microbiological quantification of Candida spp. and mutans streptococci was conducted. Results: Both propolis solution and alkaline peroxide reduced the microbial counts for S. mutans and C. albicans with significant and greater effect for group C (P< 0.05). However, no difference was found clinically between the interventions. The propolis solution showed an intermediate antimicrobial effect against S. mutans and C. albicans. Also, it did not exert an immediate effect on denture biofilm. Clinical Significance: A commercially available propolis-based cleanser solution was evaluated in vitro and clinically for the treatment of denture stomatitis. Although an immediate effect on denture biofilm was not observed after a single application, It showed antimicrobial effect against S. mutans and C. albicans. Competing Interests: The authors declared no conflict of interest. Financial support: Fundação de Amparo a Pesquisa do Estado de São Paulo-Fapesp ( grants no. 09/53788-9, 09/53789-5, 10/51382-2 and 10/09520-9). (Copyright©American Journal of Dentistry.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu