Are there different patterns of detrusor overactivity which are clinically relevant? ICI-RS 2018.

Autor: Gajewski JB; Department of Urology, Dalhousie University, Halifax, Nova Scotia, Canada., Gammie A; Bristol Urological Institute, Southmead Hospital, Bristol, UK., Speich J; Department of Mechanical and Nuclear Engineering, College of Engineering, Virginia Commonwealth University, Richmond, Virginia., Kirschner-Hermanns R; Department of Neuro-Urology, University Hospital of the Rheinische Friedrich-Wilhelms University Bonn, Bonn, Germany.; Department of Urology and Paediatric Urology, Neuro-Urology, Neurological Rehabilitation Center 'Godeshoehe e.V.', Bonn, Germany., De Wachter S; Department of Urology, University of Antwerp, Antwerp, Belgium., Schurch B; Neurourology Unit Department of Neurosciences, University Hospital Lausanne, Lausanne, Switzerland., Korstanje C; Department of Drug Discovery Science & Management, Astellas Pharma Europe BV, Leiden, The Netherlands., Valentini F; Université Pierre et Marie Curie, Hôpital Rothschild, Paris, France., Rahnama'i MS; Uniklinik Aachen RWTH, Aachen, Germany.; Maastricht University, The Netherlands.
Jazyk: angličtina
Zdroj: Neurourology and urodynamics [Neurourol Urodyn] 2019 Dec; Vol. 38 Suppl 5, pp. S40-S45.
DOI: 10.1002/nau.23964
Abstrakt: Introduction: Different patterns of detrusor overactivity (DO) have been described and included in several standardization terminology documents. However, it is unclear if these different patterns have any clinical significance.
Methods: This is a report of the proceedings of Proposal 3: "Are there different patterns of detrusor overactivity which are clinically relevant?" from the annual International Consultation on Incontinence-Research Society (ICIRS) meeting, which took place from 14 to 16 June 2018, in Bristol, UK.
Results: We have collected and discussed, as a committee, the evidence about different urodynamic (UD) patterns of detrusor overactivity and their potential clinical significance. We reviewed the important previous basic research and clinical studies and compiled summaries. The discussion focused on clinical relevance of different UD patterns of DO and what further research is required.
Conclusions: There are several UD definitions of patterns of detrusor overactivity, however the clinical relevance of these definitions remains unclear. Future research should concentrate on defining the pattern of DO in relation to clinical diagnosis, gender, age, and treatment outcomes.
(© 2019 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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