Effect of congenital toxoplasmosis on the encoding of speech in infants.

Autor: Ferreira L; Speech Therapy Department, Federal University of Santa Maria, Santa Maria, Brazil. Electronic address: laaisferreira@hotmail.com., Valadão MCDS; Medical Pediatric Infectologist, University Hospital of Santa Maria, Brazil., Skarzynski PH; Institute of Physiology and Pathology of Hearing, Warsaw, Poland; Department of Heart Failure and Cardiac Rehabilitation, Warsaw, Poland; Institute of Sensory Organs, Warsaw, Poland., Sanfins MD; State University of Campinas, Campinas, Brazil; Centro de Eletrofisiologia e Neuroaudiologia Avançada, São Paulo, Brazil., Biaggio EPV; Speech Therapy Department, Federal University of Santa Maria, Santa Maria, Brazil.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2020 Feb; Vol. 129, pp. 109767. Date of Electronic Publication: 2019 Nov 06.
DOI: 10.1016/j.ijporl.2019.109767
Abstrakt: Objective: To investigate the effect of congenital toxoplasmosis (CTP) on the Frequency-Following Response (FFR) in infants.
Study Design: 11 infants diagnosed with CTP and 12 healthy infants with no risk indicators for hearing impairment, aged 29-90 days old. All infants underwent an FFR neurophysiological assessment. The test stimulus was the syllable [da], 40 ms in duration, which was monaurally presented to the right ear at an intensity of 80 dBnHL. Absolute latencies and amplitudes of the V, A, C, D, E, F, and O waves, the slope (μV/ms) and measure between onset (A) and offset (O), were compared between the two groups.
Results: Infants with CTP had increased latency of FFR waves V, A, E, F, and O, and decreased amplitude for waves A and F. They also showed a reduction in A-O slope and a higher latency difference between onset (A) and offset (O).
Conclusion: The neurophysiological responses of Frequency-Following Response can be influenced by congenital toxoplasmosis. Since, the CTP showed prolongation of the V, A, E, F and O waves and decrease of the amplitude for waves A and F.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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