Serendipitous Treatment of Tularemia in Pregnancy.

Autor: Johnsrud JJ; Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA., Smith CR; Boston Mountain Rural Health, Bee Branch, Arkansas, USA., Bradsher RW; Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Jazyk: angličtina
Zdroj: Open forum infectious diseases [Open Forum Infect Dis] 2019 Sep 24; Vol. 6 (10), pp. ofz413. Date of Electronic Publication: 2019 Sep 24 (Print Publication: 2019).
DOI: 10.1093/ofid/ofz413
Abstrakt: We present a young pregnant woman who developed ulceroglandular tularaemia following a bite wound from a kitten. She grew Francisella tularensis from the ulcer. While awaiting bacterial culture results and serology for Bartonella , she was treated with azithromycin, with resolution of fever and axillary tenderness. Treatment recommendations for tularemia are either gentamicin or doxycycline, both of which can be perilous to the fetus. A Centers for Disease Control and Prevention report on the macrolide susceptibility of North American isolates of this organism has been underappreciated. The unanticipated result from this patient may give another potential option for treatment of tularemia in pregnancy.
(© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
Databáze: MEDLINE
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