| Autor: |
Maklakova IY; Ural State Medical University, 3 Repin str., Ekaterinburg 620028, Russian Federation, e-mail: dr-grebnev77@mail.ru.; Institute of medical cell technologies, 22a Karla Marksa str., Ekaterinburg 620026, Russian Federation., Grebnev DY; Ural State Medical University, 3 Repin str., Ekaterinburg 620028, Russian Federation, e-mail: dr-grebnev77@mail.ru.; Institute of medical cell technologies, 22a Karla Marksa str., Ekaterinburg 620026, Russian Federation., Yusupova VC; Ural State Medical University, 3 Repin str., Ekaterinburg 620028, Russian Federation, e-mail: dr-grebnev77@mail.ru., Krohalev VY; Ural State Medical University, 3 Repin str., Ekaterinburg 620028, Russian Federation, e-mail: dr-grebnev77@mail.ru. |
| Abstrakt: |
The aim of this research was to study the migration of multipotent mesenchymal stromal cells (MMSC) in old laboratory animals under physiological conditions and after liver resection. Different routes of administration were used: to the caudal vein, intraperitoneal, hepatic artery, portal vein. Studies have shown the ability of the old organism to respond to changes in the directed migration of MMSCs in the tissues that have undergone the greatest damage, which may be due to the production of connective tissue of the damaged organ chemoattractant. In contrast intraperitoneal, other delivery methods MMSC: tail vein, v. portae, a. hepatica, are more effective. |
