Effects of maternal lifestyle interventions on child neurobehavioral development: Follow-up of randomized controlled trials.

Autor: Menting MD; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., van de Beek C; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Rono K; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Hoek A; University of Groningen, University Medical Centre Groningen, Department of Obstetrics and Gynecology, Groningen, the Netherlands., Groen H; University of Groningen, University Medical Centre Groningen, Department of Epidemiology, Groningen, the Netherlands., Painter RC; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Girchenko P; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Lahti-Pulkkinen M; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.; University/British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, UK., Koivusalo SB; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Räikkönen K; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Roseboom TJ; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Heinonen K; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
Jazyk: angličtina
Zdroj: Scandinavian journal of psychology [Scand J Psychol] 2019 Dec; Vol. 60 (6), pp. 548-558. Date of Electronic Publication: 2019 Sep 09.
DOI: 10.1111/sjop.12575
Abstrakt: Obesity is a major public health problem. Children of women who were obese before or during pregnancy are at increased risk for neurobehavioral developmental problems. Whether a maternal lifestyle intervention conducted before and during pregnancy in obese women affects child neurobehavioral development is unknown. This study reports on the follow-up of a subsample of two randomized controlled trials, the Finnish RADIEL (n = 216) and Dutch LIFEstyle (n = 305) trial. Women with a pre-pregnancy BMI ≥29 kg/m 2 wishing to conceive or who were already pregnant (<20 weeks) were allocated to a lifestyle intervention or to care as usual. Child neurodevelopment was measured with the Ages and Stages Questionnaire and child behavioral problems were measured with the Childhood Behavior Checklist (RADIEL) or the Strengths and Difficulties Questionnaire (LIFEstyle) at age 3-6 years. We used linear and binary logistic regression analyses to assess the effects of the lifestyle interventions on children's neurobehavioral developmental scores. Follow-up data was available from 161(38%) RADIEL and 96(32%) LIFEstyle children. Child neurodevelopmental scores did not differ significantly between children in the intervention and the control group (RADIEL:median = 275 vs. 280; LIFEstyle:median = 270 vs 267). Child behavioral problem scores did not differ significantly between children in the intervention and the control group (RADIEL:median = 22 vs. 21; LIFEstyle:median = 8 vs. 8). We did not observe considerable effects of the lifestyle interventions before or during pregnancy in obese women on child neurobehavioral development. With our sample sizes, we were not able to detect subtle differences in neurobehavioral development however.
(© 2019 The Authors. Scandinavian Journal of Psychology published by Scandinavian Psychological Associations and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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