| Autor: |
Stanković DM; The 'Vinča' Institute of Nuclear Sciences, University of Belgrade, POB 522, Belgrade, 11001, Serbia. daliborstankovic@vin.bg.ac.rs., Jović M; Laboratory of Physical and Analytical Electrochemistry (LEPA), EPFL Valais Wallis, Rue de l'Industrie 17, CH-1951, Sion, Switzerland., Ognjanović M; The 'Vinča' Institute of Nuclear Sciences, University of Belgrade, POB 522, Belgrade, 11001, Serbia., Lesch A; Department of Industrial Chemistry 'Toso Montanari', University of Bologna, Viale del Risorgimento 4, 40136, Bologna, Italy., Fabián M; Institute of Geotechnics SAS, Watsonova 45, 040 01, Košice, Slovak Republic., Girault HH; Laboratory of Physical and Analytical Electrochemistry (LEPA), EPFL Valais Wallis, Rue de l'Industrie 17, CH-1951, Sion, Switzerland., Antić B; The 'Vinča' Institute of Nuclear Sciences, University of Belgrade, POB 522, Belgrade, 11001, Serbia. |
| Abstrakt: |
An electrochemical sensor is described for the determination of L-dopa (levodopa; 3,4-dihydroxyphenylalanine). An inkjet-printed carbon nanotube (IJPCNT) electrode was modified with manganese dioxide microspheres by drop-casting. They coating was characterized by field emission scanning electron microscopy, Fourier-transform infrared spectroscopy and X-ray powder diffraction. The sensor, best operated at a working voltage of 0.3 V, has a linear response in the 0.1 to 10 μM L-dopa concentration range, a 54 nM detection limit, excellent reproducibility, repeatability and selectivity. The amperometric approach was applied to the determination of L-dopa in spiked biological fluids and displayed satisfactory accuracy and precision. Graphical abstract Schematic representation of an amperometric method for determination L-dopa. It is based on the use of inkjet-printed carbon nanotube electrode (IJPCNT) modified with manganese dioxide (MnO 2 ). |
