Responsiveness of Oral Health-Related Quality of Life Questionnaires to Dental Caries Interventions: Systematic Review and Meta-Analysis.

Autor: Aimée NR; Faculty of Health Sciences, University of Brasília (UnB), Brasília, Brazil., Damé-Teixeira N; Faculty of Health Sciences, University of Brasília (UnB), Brasília, Brazil., Alves LS; School of Dentistry, Federal University of Santa Maria (UFSM), Santa Maria, Brazil., Borges GÁ; Faculty of Health Sciences, University of Brasília (UnB), Brasília, Brazil., Foster Page L; Faculty of Dentistry, University of Otago (UO), Dunedin, New Zealand., Mestrinho HD; Faculty of Health Sciences, University of Brasília (UnB), Brasília, Brazil., Carvalho JC; Faculty of Medicine and Dentistry, Catholic University of Louvain (UCL), Brussels, Belgium, joana.carvalho@uclouvain.be.
Jazyk: angličtina
Zdroj: Caries research [Caries Res] 2019; Vol. 53 (6), pp. 585-598. Date of Electronic Publication: 2019 Jul 05.
DOI: 10.1159/000500855
Abstrakt: This systematic review and meta-analysis were undertaken to assess the responsiveness of validated oral health-related quality of life (OHRQoL) questionnaires to dental caries interventions in children, adolescents, and young adults. Studies eligible were randomized clinical trials (RCTs), controlled clinical trials (CCTs), and prospective case series (PCS), which had OHRQoL questionnaires answered before and after caries intervention(s). The main outcome was improvement in OHRQoL mean scores following caries intervention. Twenty-six studies were selected for the quality assessment and 14 were selected for the meta-analysis. Most of the studies were PCS with a single group pretest and posttest study design (n = 19). Five studies were CCT and only 2 were RCT. The numbers of participants were 3,522 in the control group (baseline = 2,002; final = 1,520) and 5,917 in the test group (baseline = 3,102; final = 2,815). The age of the subjects ranged from 3 to 19 years. All studies showed significant improvement in OHRQoL following caries intervention. Most of nonrandomized studies (n = 15) had low or moderate risk of bias. The meta-analysis showed the effect of caries interventions (standardized weighted mean differences = -1.24; 95% CI: -1.68 to -0.81; p < 0.001). However, high heterogeneity between the studies was found. The Grading of Recommendations Assessment, Development and Evaluation approach classified the quality of evidence as very low and its strength weak. In conclusion, there is evidence that the OHRQoL of children and adolescents improved following caries intervention procedures, but the quality of the evidence was very low. In spite of that, caries interventions are highly recommended as abstaining from treatment is likely to result in a deterioration of OHRQoL.
(© 2019 S. Karger AG, Basel.)
Databáze: MEDLINE
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