| Autor: |
De Cock KM; Dept. of Medicine, Kenyatta National Hospital, Nairobi, Kenya., Awadh S, Raja RS, Wankya BM, Jupp RA, Slavin B, Arap Siongok TK, Rees PH, Bertrand J, Lucas SB |
| Jazyk: |
angličtina |
| Zdroj: |
Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 1987; Vol. 81 (1), pp. 107-10. |
| DOI: |
10.1016/0035-9203(87)90297-5 |
| Abstrakt: |
Eighty-five patients with chronic splenomegaly and proven oesophageal varices were studied at Kenyatta National Hospital, Nairobi. The major defined groups were hepatosplenic schistosomiasis (24%), cirrhosis (20%) and portal vein occlusion (11%). Hyper-reactive malarial splenomegaly (tropical splenomegaly syndrome) was considered as the cause of oesophageal varices in only one patient. In 26% of cases liver biopsy was non-diagnostic and the extrahepatic portal vein was demonstrated radiologically to be patent. Such patients were thought to be suffering from idiopathic portal hypertension, not previously described elsewhere in Africa. Hepatitis B surface antigen was detected in 12% of controls and in 58% of patients with cirrhosis (p less than 0.001). Some serological marker of previous hepatitis B virus infection was present in 92% of patients with cirrhosis and in 79% of controls. Kamba patients from Machakos and Kitui Districts were significantly more prevalent than expected among these 85 cases of portal hypertension. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
