Autor: |
Antonov AS; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation., Leshchenko EV; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation.; Far Eastern Federal University, Vladivostok, Russian Federation., Zhuravleva OI; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation.; Far Eastern Federal University, Vladivostok, Russian Federation., Dyshlovoy SA; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation.; Far Eastern Federal University, Vladivostok, Russian Federation.; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Humburg, Germany., von Amsberg G; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Humburg, Germany., Popov RS; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation., Denisenko VA; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation., Kirichuk NN; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation., Afiyatullov SS; G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russian Federation. |
Abstrakt: |
Nine naphto-γ-pyrones rubrofusarine B ( 1 ), TMC 256 A1 ( 2 ), fansecinones A ( 3 ) and B ( 4 ), aurasperones A ( 5 ), B ( 6 ) and F ( 7 ), dianhydro-aurasperone C ( 8 ) and asperpyrone B ( 9 ) were isolated from the marine-derived fungus Aspergillus foetidus KMM 4694. Their structures were established based on spectroscopic methods. The effect of the substances on viability and colony formation of human drug-resistant prostate cancer 22Rv1 cell was evaluated. |