| Autor: |
Hong CS; Duke University Medical Center, Durham, NC, USA., Ryan SP; Duke University Medical Center, Durham, NC, USA., Gabor JA; NYU Langone Health, New York City, NY, USA., Bergen MA; Duke University Medical Center, Durham, NC, USA., Schwarzkopf R; NYU Langone Health, New York City, NY, USA., Seyler TM; Duke University Medical Center, Durham, NC, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Advances in orthopedics [Adv Orthop] 2019 May 02; Vol. 2019, pp. 6521941. Date of Electronic Publication: 2019 May 02 (Print Publication: 2019). |
| DOI: |
10.1155/2019/6521941 |
| Abstrakt: |
Two-stage exchange is most commonly used for treatment of prosthetic joint infections (PJI) but, this may fail to eradicate infections. C-reactive protein/albumin ratio (CAR) has been used to predict survival and operative success in other surgical subspecialties and so, we assess the association between CAR and reimplantation success during two-stage revision for PJI defined by the Musculoskeletal Infection Society following a primary total hip (THA) or knee (TKA) arthroplasty. From January, 2005 to December, 2015, two institutional databases were queried and patient demographics, antibiotic duration, C-reactive protein, and albumin were collected prior to reimplantation. Two-stage revisions were considered successful if patients were off of antibiotics and did not require a repeat surgery. CAR was available for 79 patients (34 hips and 46 knees) with 61 successful two-stage revisions and 18 failures. The average CAR for patients with successful reimplantation was 1.2 (0.2, 3.0) compared to 1.0 (0.4, 3.2) for treatment failure. However, this was not statistically significant (p=0.766). Therefore, CAR is not applicable in predicting the prognosis of two-stage revisions for PJI in total arthroplasty but other preoperative inflammatory-based prognostic scores should be explored. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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