| Autor: |
Sherikar MS; Department of Organic Chemistry , Indian Institute of Science , Bangalore 560 012 , Karnataka , India., Prabhu KR; Department of Organic Chemistry , Indian Institute of Science , Bangalore 560 012 , Karnataka , India. |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2019 Jun 21; Vol. 21 (12), pp. 4525-4530. Date of Electronic Publication: 2019 Jun 10. |
| DOI: |
10.1021/acs.orglett.9b01412 |
| Abstrakt: |
A weakly coordinating carboxylate directing group assisted C-H activation with maleimides leading to novel and switchable decarboxylative Heck-type and [4 + 1] annulation products catalyzed by Rh(III) has been reported. In these reactions, solvents play a vital role in switching the selectivity. An aprotic solvent, THF, leads to the decarboxylative Heck-type product while the protic solvent, TFE, results in the [4 + 1] annulation product. The methodology shows high functional group tolerance. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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