A pilot study of improvised CPAP (iCPAP) via face mask for the treatment of adult respiratory distress in low-resource settings.

Autor: Milliner BH; Division of Emergency Medicine, University of Utah, 30 N 1900 E 1C026, Salt Lake City, UT, 84132, USA. Brendan.milliner@gmail.com., Bentley S; Simulation Center at Elmhurst and Department of Emergency Medicine, Elmhurst Hospital Center, Elmhurst, NY, USA.; Departments of Emergency Medicine and Medical Education, Icahn School of Medicine at Mount Sinai, 3 East 101st Street, Box 1620, New York, NY, 10029, USA., DuCanto J; Department of Anesthesiology, Aurora St. Luke's Medical Center, 2900 W Oklahoma Ave, Milwaukee, WI, 53215, USA.
Jazyk: angličtina
Zdroj: International journal of emergency medicine [Int J Emerg Med] 2019 Mar 05; Vol. 12 (1), pp. 7. Date of Electronic Publication: 2019 Mar 05.
DOI: 10.1186/s12245-019-0224-0
Abstrakt: Background: Continuous positive airway pressure (CPAP) is a mode of non-invasive ventilation used to treat a variety of respiratory conditions in the emergency department and intensive care unit. In low-resource settings where ventilators are not available, the ability to improvise a CPAP system from locally available equipment would provide a previously unavailable means of respiratory support for patients in respiratory distress. This manuscript details the design of such a system and its performance in healthy volunteers.
Methods: An improvised CPAP system was assembled from standard emergency department equipment and tested in 10 healthy volunteers (6 male, 4 female; ages 29-33). The system utilizes a water seal and high-flow air to create airway pressure; it was set to provide a pressure of 5 cmH2O for the purposes of this pilot study. Subjects used the system in a monitored setting for 30 min. Airway pressure, heart rate, oxygen saturation, and end-tidal CO2 were monitored. Comfort with the device was assessed via questionnaire.
Results: The system maintained positive airway pressure for the full trial period in all subjects, with a mean expiratory pressure (EP) of 5.1 cmH2O (SD 0.7) and mean inspiratory pressure (IP) of 3.2 cmH2O (SD 0.8). There was a small decrease in average EP (5.28 vs 4.88 cmH2O, p = 0.03) and a trend toward decreasing IP (3.26 vs 3.07 cmH2O, p = 0.22) during the trial. No significant change in heart rate, O2 saturation, respiratory rate, or end-tidal CO2 was observed. The system was well tolerated, ranked an average of 4.0 on a 1-5 scale for comfort (with 5 = very comfortable).
Conclusions: This improvised CPAP system maintained positive airway pressure for 30 min in healthy volunteers. Use did not cause tachycardia, hypoxia, or hypoventilation and was well tolerated. This system may be a useful adjunctive treatment for respiratory distress in low-resource settings. Further research should test this system in settings where other positive pressure modalities are not available.
Databáze: MEDLINE
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