[Characteristics of the inhibition of thymus endocrine function and synthesis of substances with thymosin-like activity caused by thymostimulin and splenin during DMBA-induced mammary gland carcinogenesis in rats].

Autor: Bendiug GD, Kamenets LIa, Nikol'skiĭ IS, Grinevich IuA
Jazyk: ruština
Zdroj: Eksperimental'naia onkologiia [Eksp Onkol] 1987; Vol. 9 (3), pp. 54-7.
Abstrakt: The contents of thymic hormones and endogenous substances with thymosin-like activity (TLA) was studied under conditions of administering thymostimulin and splenin during DMBA-induced carcinogenesis in rat mammary glands. It has been established that during latent carcinogenesis there is an inhibition of thymic endocrine function which persists in tumour-bearing animals. Injections of thymostimulin and splenin induce synthesis of substances with TLA, accompanied by an inhibition of blastoma development.
Databáze: MEDLINE