Whole-exome sequencing indicates FLG 2 variant associated with leg ulcers in Brazilian sickle cell anemia patients.

Autor: de Carvalho-Siqueira GQ; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil., Ananina G; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil., de Souza BB; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil., Borges MG; 2 Department of Medical Genetics and Genome Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, SP 13083-887, Brazil., Ito MT; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil., da Silva-Costa SM; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil., de Farias Domingos I; 3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil., Falcão DA; 3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil., Lopes-Cendes I; 2 Department of Medical Genetics and Genome Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, SP 13083-887, Brazil., Bezerra MAC; 3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil., da Silva Araújo A; 4 Hematology and Hemotherapy Foundation of Pernambuco, Recife, PE 52011-000, Brazil., Lucena-Araújo AR; 3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil., de Souza Gonçalves M; 5 Gonçalo Moniz Institute (Fiocruz), Salvador, BA 40296-710, Brazil., Saad STO; 6 Hematology and Hemotherapy Center, University of Campinas, Campinas, SP 13083-878, Brazil., Costa FF; 6 Hematology and Hemotherapy Center, University of Campinas, Campinas, SP 13083-878, Brazil., de Melo MB; 1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Jazyk: angličtina
Zdroj: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2019 Aug; Vol. 244 (11), pp. 932-939. Date of Electronic Publication: 2019 May 12.
DOI: 10.1177/1535370219849592
Databáze: MEDLINE