Poor long-term outcome in acute coronary syndrome in a real-life setting: Ten-year outcome of the TACOS study.

Autor:	Konttila KK; Faculty of Medicine and Health Technology, Tampere University, Tampere., Koivula K; South-Karelia Central Hospital, Finland., Eskola MJ; Heart Center, Tampere University Hospital, Finland., Martiskainen M; Faculty of Medicine and Health Technology, Tampere University, Tampere., Huhtala H; Faculty of Social Sciences, Tampere University, Finland., Virtanen VK; Heart Center, Tampere University Hospital, Finland., Mikkelsson J; Heart Center, Satakunta Central Hospital, Pori, Finland., Järvelä K; Heart Center, Tampere University Hospital, Finland., Niemelä KO; Heart Center, Tampere University Hospital, Finland., Karhunen PJ; Faculty of Medicine and Health Technology, Tampere University and Fimlab Laboratories Tampere University Hospital, Tampere, Finland., Nikus KC; Heart Center, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland. kjell.nikus@sydansairaala.fi.
Jazyk:	angličtina
Zdroj:	Cardiology journal [Cardiol J] 2021; Vol. 28 (2), pp. 302-311. Date of Electronic Publication: 2019 Apr 17.
DOI:	10.5603/CJ.a2019.0037
Abstrakt:	Background: Long-term outcome of the three categories of acute coronary syndrome (ACS) in real-life patient cohorts is not well known. The objective of this study was to survey the 10-year outcome of an ACS patient cohort admitted to a university hospital and to explore factors affecting the outcome. Methods: A total of 1188 consecutive patients (median age 73 years) with ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI) or unstable angina pectoris (UA) in 2002-2003 were included and followed up for ≥ 10 years. Results: Mortality for STEMI, NSTEMI and UA patients during the follow-up period was 52.5%, 69.9% and 41.0% (p < 0.001), respectively. In multivariable Cox regression analysis, only age and creatinine level at admission were independently associated with patient outcome in all the three ACS categories when analyzed separately. Conclusions: All the three ACS categories proved to have high mortality rates during long-term followup in a real-life patient cohort. NSTEMI patients had worse outcome than STEMI and UA patients during the whole follow-up period. Our study results indicate clear differences in the prognostic significance of various demographic and therapeutic parameters within the three ACS categories.
Databáze:	MEDLINE
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