| Autor: |
Muhammad KJ; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia , Johor Bahru, Johor, Malaysia.; Chemistry Advanced Research Centre, Sheda Science and Technology Complex , Garki , Abuja-Nigeria., Jamil S; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia , Johor Bahru, Johor, Malaysia., Basar N; Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia , Johor Bahru, Johor, Malaysia., Sarker SD; Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences, Faculty of Science, Liverpool John Moores University , Liverpool , United Kingdom., Mohammed MG; Department of Pharmacology and Therapeutics, Ahmadu Bello University , Zaria , Nigeria. |
| Abstrakt: |
Phytochemical study was conducted on the leaves of Globimetula braunii which is a hemi parasitic plant belonging to the family Loranthaceae. Extraction was carried out using cold extraction method with increasing polarity of solvents i.e n -hexane, CH 2 Cl 2 and MeOH. The components were separated by chromatographic technique and the structures of the compounds were elucidated by extensive spectroscopic analyses including MS, FTIR, 1D and 2D NMR, HRMS and chemical methods. Six new pentacyclic triterpenoid esters named as globrauneine A (1) , globrauneine B (2) , globrauneine C (3) , globrauneine D (4) , globrauneine E (5) , and globrauneine F (6), together with six known compounds (7 - 12) were successfully isolated from the leaves of G. braunii growing on Piliostigma thonningii . These results depict a substantial support to the chemotaxonomy of the genus Globimetula . |
