[Arteriovenous malformations and epileptic seizures in children: risk factors of seizures and efficacy of their control depending on the surgical treatment modality].

Autor:	Tadevosyan AR; Almazov National Medical Research Center, Saint Petersburg, Russia., Sysoev KV; Almazov National Medical Research Center, Saint Petersburg, Russia., Samochernykh KA; Almazov National Medical Research Center, Saint Petersburg, Russia., Khachatryan VA; Almazov National Medical Research Center, Saint Petersburg, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2019; Vol. 83 (1), pp. 83-89.
DOI:	10.17116/neiro2019830117583
Abstrakt:	Epileptic seizures are some of the most frequent manifestations of cerebral AVMs in children. Poor control of seizures can significantly affect patients' quality of life. In this case, factors that are associated with the development of seizures and affect the efficacy of their control upon treatment of cerebral AVMs are not well understood. Purpose: The purpose of this study was to identify risk factors for the development of epileptic seizures as well as factors associated with a seizure-free outcome of AVM treatment in children. Material and Methods: We analyzed the results of examination and treatment in 89 patients with cerebral AVMs aged 1 to 17 years. Results: Factors associated with the development of epileptic seizures in cerebral AVMs in children included male gender of the child, a large size of AVM and its superficial location, as well as localization of the pathology in the frontal and temporal lobes of the brain and draining varices. Regression of seizures after surgery was more often observed in the case of microsurgical and/or complex surgical treatment and complete exclusion of the AVM as well as in cases of rare attacks and a short course of the disease. Conclusion: Complex and microsurgical treatment of AVMs in children provides effective control of epileptic seizures, which is obviously associated with complete exclusion of the AVM and removal of the epileptic focus located near the AVM.
Databáze:	MEDLINE
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