Heart rate variability in patients with agoraphobia with or without panic disorder remains stable during CBT but increases following in-vivo exposure.

Autor: Mumm JLM; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: Jennifer.mumm@charite.de., Pyrkosch L; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: Lena.pyrkosch@charite.de., Plag J; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: Jens.plag@charite.de., Nagel P; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Cardiology, Charité Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany. Electronic address: Patrick.nagel@charite.de., Petzold MB; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: Moritz.petzold@charite.de., Bischoff S; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: Sophie.bischoff@charite.de., Fehm L; Zentrum für Psychotherapie, Institut für Psychologie, Humboldt-Universität zu Berlin, Klosterstr. 64, 10179 Berlin, Germany. Electronic address: Lydia.fehm@hu-berlin.de., Fydrich T; Zentrum für Psychotherapie, Institut für Psychologie, Humboldt-Universität zu Berlin, Klosterstr. 64, 10179 Berlin, Germany. Electronic address: fydrich@hu-berlin.de., Ströhle A; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: andreas.stroehle@charite.de.
Jazyk: angličtina
Zdroj: Journal of anxiety disorders [J Anxiety Disord] 2019 May; Vol. 64, pp. 16-23. Date of Electronic Publication: 2019 Mar 04.
DOI: 10.1016/j.janxdis.2019.03.001
Abstrakt: Patients with anxiety disorders have a lower heart rate variability (HRV) than healthy controls. Low HRV is associated with cardiovascular disease and dysfunction of the autonomic nervous system (ANS). The aim of the present study was to investigate if HRV in patients with agoraphobia with or without panic disorder can be influenced by cognitive behavioral therapy (CBT). 73 patients with agoraphobia with or without panic disorder were included in the study. Heart rate (HR) and HRV were recorded at rest before and after CBT and during in-vivo exposure. No changes in HR and HRV were observed throughout therapy. During in-vivo exposure HRV increased significantly and HR exhibited a tendency to decrease. Despite clinical improvement of anxiety symptoms, ANS activity at rest did not seem to be influenced by CBT. However, during in-vivo exposure, HRV changed significantly, indicating a higher parasympathetic activity at the end of exposure.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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