[Cell therapy for ischemic stroke. Results of clinical trials and perspectives of clinical application in the Russian Federation].

Autor:	Namestnikova DD; Pirogov Russian National Research Medical University, Moscow, Russia., Tairova RT; Federal Center of Cererbrovascular Pathology and Stroke, Pirogov Russian National Research Medical University, Moscow, Russia., Cherkashova EA; Pirogov Russian National Research Medical University, Moscow, Russia., Sukhinich KK; Koltzov Institute of Developmental Biology, Moscow, Russia., Gubskiy IL; Federal Center of Cererbrovascular Pathology and Stroke, Pirogov Russian National Research Medical University, Moscow, Russia., Gubskiy LV; Pirogov Russian National Research Medical University, Moscow, Russia; Federal Center of Cererbrovascular Pathology and Stroke, Pirogov Russian National Research Medical University, Moscow, Russia., Yarygin KN; Orekhovich Institute of Biomedical Chemistry, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2018; Vol. 118 (12. Vyp. 2), pp. 94-104.
DOI:	10.17116/jnevro201811812294
Abstrakt:	The first part of the review summarized the results of preclinical animal studies using stroke models that demonstrated the efficacy of cell therapy. The second part presents the proposed mechanisms of action of stem cells, optimal therapeutic window for cell transplantation, the results of completed clinical trials on humans in the period from 2010 to 2017, as well as the legal aspects of the use of cell technologies in the Russian Federation.
Databáze:	MEDLINE
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