A comparison of sufentanil vs. remifentanil in fast-track cardiac surgery patients.

Autor: Zakhary WZA; Department of Anaesthesiology and Intensive Care Medicine, Heart Center Leipzig, Leipzig, Germany., Turton EW; Department of Anaesthesiology and Intensive Care Medicine, Heart Center Leipzig, Leipzig, Germany., Flo Forner A; Department of Anaesthesiology and Intensive Care Medicine, Heart Center Leipzig, Leipzig, Germany., von Aspern K; University Department for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany., Borger MA; University Department for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany., Ender JK; Department of Anaesthesiology and Intensive Care Medicine, Heart Center Leipzig, Leipzig, Germany.
Jazyk: angličtina
Zdroj: Anaesthesia [Anaesthesia] 2019 May; Vol. 74 (5), pp. 602-608. Date of Electronic Publication: 2019 Jan 20.
DOI: 10.1111/anae.14572
Abstrakt: We retrospectively compared patients receiving remifentanil with patients receiving sufentanil undergoing fast-track cardiac surgery. After 1:1 propensity score matching there were 609 patients in each group. The sufentanil group had a significantly longer mean (SD) ventilation time compared with the remifentanil group; 122 (59) vs. 80 (44) min, p < 0.001 and longer mean (SD) length of stay in the recovery area; 277 (77) vs. 263 (78) min, p = 0.002. The sufentanil group had a lower mean (SD) visual analogue pain score than the remifentanil group; 1.5 (1.2) vs. 2.4 (1.5), p < 0.001 and consumed less mean (SD) piritramide (an opioid analgesic used in our hospital); 2.6 (4.7) vs. 18.9 (7.3) mg, p < 0.001. The results of our study show that although remifentanil was more effective in reducing time to tracheal extubation and length of stay in the recovery area, there was an increased requirement for postoperative analgesia when remifentanil was used.
(© 2019 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.)
Databáze: MEDLINE
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