Association of raised blood lead levels in pregnant women with preeclampsia: A study at tertiary centre.

Autor: Disha; II Year AIIMS, Jodhpur, India., Sharma S; Department of Biochemistry All India Institute of Medical Sciences, Jodhpur, India., Goyal M; Department of Obstetrics & Gynecology All India Institute of Medical Sciences, Jodhpur, India. Electronic address: drmanu_8@yahoo.co.in., Kumar PK; Department of Biochemistry All India Institute of Medical Sciences, Jodhpur, India., Ghosh R; Department of Biochemistry All India Institute of Medical Sciences, Jodhpur, India., Sharma P; Department of Biochemistry All India Institute of Medical Sciences, Jodhpur, India.
Jazyk: angličtina
Zdroj: Taiwanese journal of obstetrics & gynecology [Taiwan J Obstet Gynecol] 2019 Jan; Vol. 58 (1), pp. 60-63.
DOI: 10.1016/j.tjog.2018.11.011
Abstrakt: Objective: This study aims to find the blood lead levels in pregnant women and its association with pre-eclampsia.
Material and Methods: The study included 44 healthy pregnant females and 23 pre-eclamptic women. Demographic data and common risk factors for lead toxicity were recorded including age, residence, occupation, husband occupation, passive smoking, use of cosmetics, kajal, surma, receiving supplements/vitamins, history of house remodelling, plumbing, source of potable water, paint in house, use of lead-glazed ceramic and pica. Venous blood was collected and lead level was determined by atomic absorption spectrometry.
Results: The mean blood lead level was 2.38 ± 2.43 ug/dL in controls and 3.42 ± 2.18 ug/dL in preeclamptic women which was significantly higher (p = 0.0132). Strong correlation of BLL was observed with blood pressure in pre-eclamptic women. Pre-eclamptic patients were observed to be at increased risk of being lead exposed in terms of occupation and living conditions.
Conclusion: Higher blood lead level is associated with increased risk of preeclampsia. Patients should be counselled for lifestyle modification to prevent complications.
(Copyright © 2018. Published by Elsevier B.V.)
Databáze: MEDLINE