FISHing for β Cells.
| Autor: | Hudish LI; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA., Lorberbaum DS; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA., Sussel L; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA. Electronic address: lori.sussel@ucdenver.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Developmental cell [Dev Cell] 2019 Jan 07; Vol. 48 (1), pp. 7-8. |
| DOI: | 10.1016/j.devcel.2018.12.007 |
| Abstrakt: | β cell heterogeneity has emerged as an important contributor to islet function, with potential implications for diabetes. Using an optimized smFISH technique in intact islets, Farack et al. (2018) identify in the islet core an endocrine cell population of "extreme" β cells with distinct molecular properties. (Copyright © 2018 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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