Haemato-immunological studies in ZnO and TiO 2 nanoparticles exposed euryhaline fish, Oreochromis mossambicus.

Autor: Suganthi P; Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India., Murali M; Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India., Athif P; Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India., Sadiq Bukhari A; Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India. Electronic address: abjmc@yahoo.in., Syed Mohamed HE; Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India., Basu H; Analytical Spectroscopy Section, Analytical Chemistry Division, Bhabha Atomic Research Center, Trombay, Mumbai 400085, India., Singhal RK; Analytical Spectroscopy Section, Analytical Chemistry Division, Bhabha Atomic Research Center, Trombay, Mumbai 400085, India.
Jazyk: angličtina
Zdroj: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2019 Feb; Vol. 66, pp. 55-61. Date of Electronic Publication: 2018 Dec 19.
DOI: 10.1016/j.etap.2018.12.011
Abstrakt: The present study was aimed to analyze the effect of ZnO and TiO 2 nanoparticles (NPs) on Haemato-immunological parameters in adult Tilapia, Oreochromis mossambicus. The nanoparticles size found as 47 nm and 30 nm for ZnO and TiO 2 respectively. The acute toxicity (96 h) of ZnO (LC50: 100-110 ppm) and TiO 2 (LC50: 80-90 ppm) NPs were identified by using probit analysis. RBC, Hb and HCT levels decreased in nanoparticles exposed groups resulted in decreased oxygen carrying capacity of RBC and other erythrocyte indices (MCH, MCV, MCHC). Increased WBC, neutrophils & monocytes and decreased lymphocyte levels were observed as increased concentration of the nanoparticles. The results were found as statistically significant (p < 0.05). In conclusion, the present study depicts that ZnO NPs exhibits more toxicity than TiO 2 NPs. Nanoparticles presence even in low concentration (ppm) cause damage to the connective tissues of fish, so the existing permissible levels of these nanoparticles in water are need to be revised.
(Copyright © 2018 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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