Which is the Best Imaging Method in Pancreatic Adenocarcinoma Diagnosis and Staging - CT, MRI or EUS?

Autor: Costache MI; Department of Gastroenterology, Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania.; Department of Radiology and Medical Imaging, University of Medicine and Pharmacy Craiova, Romania., Costache CA; Department of Neurology, University of Medicine and Pharmacy Craiova, Romania., Dumitrescu CI; Department of Pharmacology, University of Medicine and Pharmacy of Craiova, Romania., Tica AA; Department of Pharmacology, University of Medicine and Pharmacy of Craiova, Romania., Popescu M; Department of Radiology and Medical Imaging, University of Medicine and Pharmacy Craiova, Romania.; Department of Radiology and Medical Imaging, Clinical Emergency County Hospital, Craiova, Romania., Baluta EA; Department of Radiology and Medical Imaging, Clinical Emergency County Hospital, Craiova, Romania., Anghel AC; Department of Radiology and Medical Imaging, Clinical Emergency County Hospital, Craiova, Romania., Saftoiu A; Department of Gastroenterology, Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania.; Department of Endoscopy, Gastro-Unit, Copenhagen University Hospital Herlev, Denmark., Dumitrescu D; Department of Radiology and Medical Imaging, University of Medicine and Pharmacy Craiova, Romania.; Department of Radiology and Medical Imaging, Clinical Emergency County Hospital, Craiova, Romania.
Jazyk: angličtina
Zdroj: Current health sciences journal [Curr Health Sci J] 2017 Apr-Jun; Vol. 43 (2), pp. 132-136. Date of Electronic Publication: 2017 Jun 29.
DOI: 10.12865/CHSJ.43.02.05
Abstrakt: Introduction: Imaging has a decisive role in the diagnosis and staging of pancreatic cancer, the most used imaging methods being computed tomography, magnetic resonance imaging and endoscopic ultrasonography.
Material and Method: They were studied retrospectively over a 3 years period, 140 patients with pancreatic cancer.
Aim of the Study: This study aims to determine the effectiveness of CT, MRI and EUS in diagnosis and staging of panceatic cancer.
Results: CT showed a diagnostic accuracy of 83.3%, with sensitivity and specificity of 81.4% and 43% respectively. MRI showed superior diagnostic accuracy compared to CT (89,1%). However, EUS demonstrated the best diagnostic value in PC (accuracy of 92,7%). Concerning the locoregional staging, the 3 diagnostic methods showed similar result. There were no significant differences concerning the diagnosis of intra-abdominal metastases. Differences have appeared in the case of extra-abdominal. Thus, there were 4 cases of lung metastases which have been identified only on CT and MRI.
Conclusion: EUS is the most effective technique used in the diagnosis of pancreatic cancer, the present study demonstrating an accuracy of 92.7%. Moreover, EUS offers the possibility to collect samples for cytological examination by EUS guided fine needle aspiration. However, there are some limitations of EUS in identifying extra-abdominal metastases. Thus, the assessment of tumor extension must be completing by performing CT or MRI.
Databáze: MEDLINE
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