[Possibilities of retention of work capacity in patients with Parkinson's disease].

Autor:	Gankina OA; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Vasenina EE; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Pokhabov DD; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia., Voronov DB; Regional Clinical and Diagnostic Center, Rostov-on-Don, Russia., Zhukova IA; Sibirian State Medical University, Tomsk, Russia., Baitimerov AR; Kuvatov Republican Clinical Hospital, Ufa, Russia., Radyuk MA; Volgograd Medical University, Volgograd, Russia., Bojenkina TV; Federal Sibirian Research Center, Krasnoyarsk, Russia., Razdorskaya VV; Razumovsky Saratov State Medical University, Saratov, Russia., Levin OS; Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2018; Vol. 118 (6. Vyp. 2), pp. 95-98.
DOI:	10.17116/jnevro201811806295
Abstrakt:	Aim: To study the efficacy of replacement of the single daily dose of two-component levodopa by three-component levodopa in work capable patients with Parkinson's disease with motor fluctuations during the most active working hours. Material and Methods: The study included 157 patients from 19 Russian centers specialized in extrapyramidal pathology. The period of highest working activity was analyzed in all patients. In these patients, the previous treatment with two-component levodopa was replaced by three-component levodopa in the equivalent dose. Other antiparkinsonian treatment remained unchanged during the study period. The duration of the study was 1 month. Results and Conclusion: The single replacement of two-component levodopa by stalevo allows increasing the optimal working activity by 19% and improving patient's state.
Databáze:	MEDLINE
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