Primary cutaneous lymphoma in Argentina: a report of a nationwide study of 416 patients.

Autor: Abeldaño A; Hospital Gral. de Agudos Dr. C. Argerich, Ciudad de Buenos Aires, Argentina., Enz P; Hospital Italiano de Buenos Aires, Ciudad de Buenos Aires, Argentina., Maskin M; Hospital Gral. de Agudos Dr. C. Argerich, Ciudad de Buenos Aires, Argentina., Cervini AB; Hospital de Pediatría Prof. Dr. J.P. Garrahan, Ciudad de Buenos Aires, Argentina., Torres N; Hospital de Pediatría Prof. Dr. J.P. Garrahan, Ciudad de Buenos Aires, Argentina., Acosta AC; Hospital Gral. de Agudos Dr. J.M. Ramos Mejia, Ciudad de Buenos Aires, Argentina., Narbaitz M; Academia Nacional de Medicina, Ciudad de Buenos Aires, Argentina., Vanzulli S; Academia Nacional de Medicina, Ciudad de Buenos Aires, Argentina., Orentrajch M; Academia Nacional de Medicina, Ciudad de Buenos Aires, Argentina., Villareal MA; Hospital Privado de Córdoba, Ciudad de Córdoba, Argentina., Garcia Pazos ML; Psoriahue, Ciudad de Buenos Aires, Argentina., Arias M; Hospital Gral. de Agudos Dr. C. Argerich, Ciudad de Buenos Aires, Argentina., Zambrano Franco EA; Hospital Italiano de Buenos Aires, Ciudad de Buenos Aires, Argentina., Fontana MI; Policlínico Bancario, Ciudad de Buenos Aires, Argentina., Chuit R; Academia Nacional de Medicina, Ciudad de Buenos Aires, Argentina.
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2019 Apr; Vol. 58 (4), pp. 449-455. Date of Electronic Publication: 2018 Oct 07.
DOI: 10.1111/ijd.14262
Abstrakt: Background: The aim of this study was to determine the relative frequency of primary cutaneous lymphoma (PCL) in Argentina according to the new World Health Organization (WHO)-European Organization for the Research and Treatment of Cancer (EORTC) classification system.
Methods: A total of 416 patients from 21 dermatology services were included during a 5-year period (2010-2015); these patients were classified using WHO-EORTC criteria.
Results: There were 231 (55.2%) males and 185 (44.8%) females; the male-to-female ratio was 1.35. The median age of the patients was 57 years (range, 0-90 years). Most patients were Caucasian (79%), and only 16% of patients were registered as Amerindian. Most patients (387/416, 93%) had cutaneous T-cell lymphoma (CTCL); 28 patients (6.7%) were diagnosed with cutaneous B-cell lymphoma (CBCL). The most frequent CTCL subtypes, in decreasing order of prevalence, were mycosis fungoides (MF), including its variants (75.7%); CD30+ primary cutaneous lymphoproliferative disorders (7.2%); and Sézary syndrome (SS) (3.1%). Cutaneous follicle center lymphoma was the most common CBCL subtype (2.9%). In the subset of patients ≤20 years of age, the most common condition was MF (57%), followed by extranodal NK-T nasal-type lymphoma (14%).
Conclusions: This study revealed relatively higher rates of MF and lower rates of CBCL in Argentinean patients that have been reported in American and European countries.
(© 2018 The International Society of Dermatology.)
Databáze: MEDLINE
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