Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome.

Autor: Chandran RS; Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India., Patil AK; Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India., Prabhakar RB; Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India., Balachandran K; Department of Pathology, Government Medical College, Thiruvananthapuram, Kerala, India.
Jazyk: angličtina
Zdroj: Asian journal of neurosurgery [Asian J Neurosurg] 2018 Jul-Sep; Vol. 13 (3), pp. 881-884.
DOI: 10.4103/ajns.AJNS_353_16
Abstrakt: Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE
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