Delayed Post-hypoxic Leukoencephalopathy (DPHL)-An Uncommon Variant of Hypoxic Brain Damage in Adults.

Autor: Beeskow AB; Department of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany., Oberstadt M; Department of Neurology, University Hospital Leipzig, Leipzig, Germany., Saur D; Department of Neurology, University Hospital Leipzig, Leipzig, Germany., Hoffmann KT; Department of Neuroradiology, University Hospital Leipzig, Leipzig, Germany., Lobsien D; Department of Neuroradiology, University Hospital Leipzig, Leipzig, Germany.
Jazyk: angličtina
Zdroj: Frontiers in neurology [Front Neurol] 2018 Aug 27; Vol. 9, pp. 708. Date of Electronic Publication: 2018 Aug 27 (Print Publication: 2018).
DOI: 10.3389/fneur.2018.00708
Abstrakt: Delayed post-hypoxic leukoencephalopathy (DPHL) is an uncommon, potentially under-recognized, cause of hypoxia induced white matter injury. It characteristically follows a biphasic course: After an initial phase of altered neurologic status a recovery occurs which is then followed by a recurring phase of neurologic deterioration, typically 2-4 weeks after the initial event. At this time white matter changes can be identified on MRI, which are the hallmark of DPHL. The characteristics and the typical MR-imaging signs of DPHL are discussed in this case report.
Databáze: MEDLINE