Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study.

Autor: Solomon FB; Department of Medical Laboratory, Wolaita Sodo University, Wolaita Sodo, Ethiopia. fitha2007@yahoo.com., Angore BN; Department of Midwifery, College of Health Science and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Koyra HC; Department of Pharmacy, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Tufa EG; Department of Human Nutrition and Reproductive Health, School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Berheto TM; Department of Human Nutrition and Reproductive Health, School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia., Admasu M; School of Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2018 Aug 20; Vol. 11 (1), pp. 604. Date of Electronic Publication: 2018 Aug 20.
DOI: 10.1186/s13104-018-3707-9
Abstrakt: Objectives: The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART.
Results: A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76-5.66], CD4 level [AOR = 2.53:95% CI 1.19-5.37], drug adherence [AOR = 3.02:95% CI 1.57-5.77] and hemoglobin [AOR = 2.49:95% CI 1.34-4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory.
Databáze: MEDLINE
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