Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study.

Autor: Aquino SLS; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil., da Cunha ATO; 2Postgraduate Program in Health Sciences, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59012-570 Brazil., Pereira HT; 2Postgraduate Program in Health Sciences, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59012-570 Brazil., Freitas EPS; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil., Fayh APT; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil.; 3Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil., Lima JG; 4Department of Clinical Medicine, Endocrine Unit, Federal University of Rio Grande do Norte, Natal, RN 59010-180 Brazil., Lima SCVC; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil.; 3Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil., Sena-Evangelista KCM; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil.; 3Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil., Pedrosa LFC; 1Postgraduate Nutrition Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil.; 3Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, RN 59078-970 Brazil.
Jazyk: angličtina
Zdroj: Diabetology & metabolic syndrome [Diabetol Metab Syndr] 2018 Jun 04; Vol. 10, pp. 45. Date of Electronic Publication: 2018 Jun 04 (Print Publication: 2018).
DOI: 10.1186/s13098-018-0346-1
Abstrakt: Background: The risk of metabolic syndrome can be influenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the influence of environmental, biological, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome.
Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and calcium and vitamin D intake.
Results: The average vitamin D in individuals evaluated in summer 32 ± 10 ng/mL was greater than in the winter 26 ± 8 ng/mL (p < 0.017). HDL-cholesterol was the only component of the MetS that differed significantly between the seasons (p < 0.001), showing higher concentrations in autumn 45 ± 8 mg/dL than in summer 35 ± 8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p = 0.004).
Conclusions: Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that differed significantly between the seasons.
Databáze: MEDLINE
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