Refractory Hyperlactatemia After a Septic Shock in a Patient With Carnitine Deficiency: A Case Report.

Autor:	Hogan P; Faculté de pharmacie, Université de Montréal, Montréal, Quebec, Canada.; Department of pharmacy, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada., Plourde R; Faculté de pharmacie, Université de Montréal, Montréal, Quebec, Canada.; Department of pharmacy, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada., Fortier M; Faculté de pharmacie, Université de Montréal, Montréal, Quebec, Canada.; Department of pharmacy, Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada., Brindamour D; Department of pharmacy, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada., Lagrenade-Verdant C; Faculté de médecine, Université de Montréal, Montréal, Quebec, Canada.; Department of critical care, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada., Demers-Marcil S; Faculté de médecine, Université de Montréal, Montréal, Quebec, Canada., Dupuis S; Department of pharmacy, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada.; Research center, Hôpital du Sacré-Cœur-de-Montréal, Montréal, Quebec, Canada.
Jazyk:	angličtina
Zdroj:	Journal of pharmacy practice [J Pharm Pract] 2020 Feb; Vol. 33 (1), pp. 113-116. Date of Electronic Publication: 2018 Jun 15.
DOI:	10.1177/0897190018782012
Abstrakt:	A 56-year-old woman with septic shock presented with persistent hyperlactatemia, despite an adequate clinical response to treatment. Carnitine deficiency was suspected, as the patient was malnourished and chronically taking valproic acid. No other plausible cause of hyperlactatemia was found. Carnitine supplementation resulted in rapid normalization of lactatemia.
Databáze:	MEDLINE
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