Predictors of Willingness to Participate in Biospecimen Donation and Biobanking among Appalachian Adults.
| Autor: | Llanos AA, Young GS, Baltic R, Lengerich EJ, Aumiller BB, Dignan MB, Paskett ED |
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| Jazyk: | angličtina |
| Zdroj: | Journal of health care for the poor and underserved [J Health Care Poor Underserved] 2018; Vol. 29 (2), pp. 743-766. |
| DOI: | 10.1353/hpu.2018.0056 |
| Abstrakt: | Background: Rural residents in the U.S., particularly residents of Appalachia, are underrepresented in biomedical research, limiting the generalizability of research findings. Objective: To examine factors associated with Appalachian adults' willingness to participate in biospecimen donation and banking. Methods: A survey assessing willingness to donate blood, saliva, and buccal specimens and to have these biospecimens stored for future use in genetic studies was conducted among 493 Appalachian adults. Results: Most participants 73% (358/493) were willing to donate one or more biospecimen type; among them, 75% (268/358) were willing to donate blood, saliva, and buccal specimens. Approximately 61% (300/493) were willing to have their biospecimens banked and 97% (290/300) of these were willing to have their samples used for genetic studies. Appalachian self-identity predicted willingness to donate biospecimens, to have them stored, and used in genetic studies (OR1.52, 95% CI 1.03-2.24). Conclusions: Appalachian adults were generally willing to participate in biobanking research. |
| Databáze: | MEDLINE |
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