Gestational Trophoblastic Neoplasia after Ectopic Molar Pregnancy: Clinical, Diagnostic, and Therapeutic Aspects.

Autor:	López CL; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil., Lopes VGS; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil., Resende FR; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil., Steim JL; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil., Padrón L; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil.; Rio de Janeiro Trophoblastic Disease Center, Associação Brasileira de Doença Trofoblástica Gestacional, Rio de Janeiro, RJ, Brazil., Sun SY; Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Araujo Júnior E; Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Braga A; Department of Pathology, Universidade Federal Fluminense, Niterói, RJ, Brazil.; Rio de Janeiro Trophoblastic Disease Center, Associação Brasileira de Doença Trofoblástica Gestacional, Rio de Janeiro, RJ, Brazil.; Department of Gynecology and Obstetrics, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Jazyk:	angličtina
Zdroj:	Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2018 May; Vol. 40 (5), pp. 294-299. Date of Electronic Publication: 2018 May 16.
DOI:	10.1055/s-0038-1653976
Abstrakt:	This report presents the case of a patient with gestational trophoblastic neoplasia after a partial hydatidiform mole formed in the Fallopian tube. Ectopic molar pregnancy is a rare condition, with an estimated incidence of 1 in every 20,000 to 100,000 pregnancies; less than 300 cases of it have been reported in the Western literature. The present report is important because it presents current diagnostic criteria for this rare condition, which has been incorrectly diagnosed in the past, not only morphologically but also immunohistochemically. It also draws the attention of obstetricians to the occurrence of ectopic molar pregnancy, which tends to progress to Fallopian tube rupture more often than in cases of ectopic non-molar pregnancy. Progression to gestational trophoblastic neoplasia ensures that patients with ectopic molar pregnancy must undergo postmolar monitoring, which must be just as thorough as that of patients with intrauterine hydatidiform moles, even if chemotherapy results in high cure rates. Competing Interests: The authors have no conflicts of interest to declare. (Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil.)
Databáze:	MEDLINE
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