Consensus guidelines for the use and interpretation of angiogenesis assays.

Autor: Nowak-Sliwinska P; Molecular Pharmacology Group, School of Pharmaceutical Sciences, Faculty of Sciences, University of Geneva, University of Lausanne, Rue Michel-Servet 1, CMU, 1211, Geneva 4, Switzerland. Patrycja.Nowak-Sliwinska@unige.ch.; Translational Research Center in Oncohaematology, University of Geneva, Geneva, Switzerland. Patrycja.Nowak-Sliwinska@unige.ch., Alitalo K; Wihuri Research Institute and Translational Cancer Biology Program, University of Helsinki, Helsinki, Finland., Allen E; Laboratory of Tumor Microenvironment and Therapeutic Resistance, Department of Oncology, VIB-Center for Cancer Biology, KU Leuven, Louvain, Belgium., Anisimov A; Wihuri Research Institute and Translational Cancer Biology Program, University of Helsinki, Helsinki, Finland., Aplin AC; Department of Pathology, University of Washington, Seattle, WA, USA., Auerbach R; University of Wisconsin, Madison, WI, USA., Augustin HG; European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center, Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany., Bates DO; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK., van Beijnum JR; Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands., Bender RHF; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA., Bergers G; Laboratory of Tumor Microenvironment and Therapeutic Resistance, Department of Oncology, VIB-Center for Cancer Biology, KU Leuven, Louvain, Belgium.; Department of Neurological Surgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Bikfalvi A; Angiogenesis and Tumor Microenvironment Laboratory (INSERM U1029), University Bordeaux, Pessac, France., Bischoff J; Vascular Biology Program and Department of Surgery, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA., Böck BC; European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center, Heidelberg, Germany.; German Cancer Consortium, Heidelberg, Germany., Brooks PC; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, USA., Bussolino F; Department of Oncology, University of Torino, Turin, Italy.; Candiolo Cancer Institute-FPO-IRCCS, 10060, Candiolo, Italy., Cakir B; Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium., Castranova D; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Cimpean AM; Department of Microscopic Morphology/Histology, Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania., Cleaver O; Department of Molecular Biology, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Coukos G; Ludwig Institute for Cancer Research, Department of Oncology, University of Lausanne, Lausanne, Switzerland., Davis GE; Department of Medical Pharmacology and Physiology, University of Missouri, School of Medicine and Dalton Cardiovascular Center, Columbia, MO, USA., De Palma M; School of Life Sciences, Swiss Federal Institute of Technology, Lausanne, Switzerland., Dimberg A; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Dings RPM; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Djonov V; Institute of Anatomy, University of Bern, Bern, Switzerland., Dudley AC; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA.; Emily Couric Cancer Center, The University of Virginia, Charlottesville, VA, USA., Dufton NP; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, London, UK., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute, Leuven, Belgium., Ferrara N; University of California, San Diego, La Jolla, CA, USA., Fruttiger M; Institute of Ophthalmology, University College London, London, UK., Fukumura D; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ghesquière B; Metabolomics Expertise Center, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Oncology, Metabolomics Expertise Center, KU Leuven, Leuven, Belgium., Gong Y; Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA., Griffin RJ; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Harris AL; Molecular Oncology Laboratories, Oxford University Department of Oncology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK., Hughes CCW; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA., Hultgren NW; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA., Iruela-Arispe ML; MCDB, University of California, Los Angeles, CA, USA., Irving M; Ludwig Institute for Cancer Research, Department of Oncology, University of Lausanne, Lausanne, Switzerland., Jain RK; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kalluri R; Department of Cancer Biology, Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kalucka J; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium., Kerbel RS; Department of Medical Biophysics, Biological Sciences Platform, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada., Kitajewski J; Department of Physiology and Biophysics, University of Illinois, Chicago, IL, USA., Klaassen I; Ocular Angiogenesis Group, Departments of Ophthalmology and Medical Biology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Kleinmann HK; The George Washington University School of Medicine, Washington, DC, USA., Koolwijk P; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland., Kuczynski E; Department of Medical Biophysics, Biological Sciences Platform, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada., Kwak BR; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Marien K; HistoGeneX, Antwerp, Belgium., Melero-Martin JM; Department of Cardiac Surgery, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA., Munn LL; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Nicosia RF; Department of Pathology, University of Washington, Seattle, WA, USA.; Pathology and Laboratory Medicine Service, VA Puget Sound Health Care System, Seattle, WA, USA., Noel A; Laboratory of Tumor and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium., Nurro J; Department of Biotechnology and Molecular Medicine, University of Eastern Finland, Kuopio, Finland., Olsson AK; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala Biomedical Center, Uppsala University, Uppsala, Sweden., Petrova TV; Department of oncology UNIL-CHUV, Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Pietras K; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund, Sweden., Pili R; Genitourinary Program, Indiana University-Simon Cancer Center, Indianapolis, IN, USA., Pollard JW; Medical Research Council Centre for Reproductive Health, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK., Post MJ; Department of Physiology, Maastricht University, Maastricht, The Netherlands., Quax PHA; Einthoven Laboratory for Experimental Vascular Medicine, Department Surgery, LUMC, Leiden, The Netherlands., Rabinovich GA; Laboratory of Immunopathology, Institute of Biology and Experimental Medicine, National Council of Scientific and Technical Investigations (CONICET), Buenos Aires, Argentina., Raica M; Department of Microscopic Morphology/Histology, Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania., Randi AM; Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, London, UK., Ribatti D; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy.; National Cancer Institute 'Giovanni Paolo II', Bari, Italy., Ruegg C; Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland., Schlingemann RO; Ocular Angiogenesis Group, Departments of Ophthalmology and Medical Biology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland., Schulte-Merker S; Institute of Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU, Münster, Germany., Smith LEH; Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA., Song JW; Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH, USA.; Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Stacker SA; Tumour Angiogenesis and Microenvironment Program, Peter MacCallum Cancer Centre and The Sir Peter MacCallum, Department of Oncology, University of Melbourne, Melbourne, VIC, Australia., Stalin J; Institute of Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU, Münster, Germany., Stratman AN; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Van de Velde M; Laboratory of Tumor and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium., van Hinsbergh VWM; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland., Vermeulen PB; HistoGeneX, Antwerp, Belgium.; Translational Cancer Research Unit, GZA Hospitals, Sint-Augustinus & University of Antwerp, Antwerp, Belgium., Waltenberger J; Medical Faculty, University of Münster, Albert-Schweitzer-Campus 1, Münster, Germany., Weinstein BM; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Xin H; University of California, San Diego, La Jolla, CA, USA., Yetkin-Arik B; Ocular Angiogenesis Group, Departments of Ophthalmology and Medical Biology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Yla-Herttuala S; Department of Biotechnology and Molecular Medicine, University of Eastern Finland, Kuopio, Finland., Yoder MC; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Griffioen AW; Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. aw.griffioen@vumc.nl.
Jazyk: angličtina
Zdroj: Angiogenesis [Angiogenesis] 2018 Aug; Vol. 21 (3), pp. 425-532.
DOI: 10.1007/s10456-018-9613-x
Abstrakt: The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.
Databáze: MEDLINE