| Autor: |
Dodzian J; Max Planck Institute for the Biology of Ageing; International Institute of Molecular and Cell Biology in Warsaw., Kean S; Max Planck Institute for the Biology of Ageing., Seidel J; Max Planck Institute for the Biology of Ageing., Valenzano DR; Max Planck Institute for the Biology of Ageing; CECAD, University of Cologne; dvalenzano@age.mpg.de. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of visualized experiments : JoVE [J Vis Exp] 2018 Apr 11 (134). Date of Electronic Publication: 2018 Apr 11. |
| DOI: |
10.3791/57073 |
| Abstrakt: |
The development of husbandry practices in non-model laboratory fish used for experimental purposes has greatly benefited from the establishment of reference fish model systems, such as zebrafish and medaka. In recent years, an emerging fish - the turquoise killifish (Nothobranchius furzeri) - has been adopted by a growing number of research groups in the fields of biology of aging and ecology. With a captive life span of 4 - 8 months, this species is the shortest-lived vertebrate raised in captivity and allows the scientific community to test - in a short time - experimental interventions that can lead to alterations of the aging rate and life expectancy. Given the unique biology of this species, characterized by embryonic diapause, explosive sexual maturation, marked morphological and behavioral sexual dimorphism - and their relatively short adult life span - ad hoc husbandry practices are in urgent demand. This protocol reports a set of key husbandry measures that allow optimal turquoise killifish laboratory care, enabling the scientific community to adopt this species as a powerful laboratory animal model. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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