Tissue Motion Annular Displacement Predicts Mortality/Transplant After the Bidirectional Glenn.

Autor:	Penk JS; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA., Zaidi SJH; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA., Lefaiver CA; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA., Muangmingsuk S; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA., Cui VW; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA., Roberson DA; 1 Department of Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA.
Jazyk:	angličtina
Zdroj:	World journal for pediatric & congenital heart surgery [World J Pediatr Congenit Heart Surg] 2018 Mar; Vol. 9 (2), pp. 171-176.
DOI:	10.1177/2150135117742650
Abstrakt:	Background: Quantifying right ventricular function in patients with a systemic right ventricle (RV) is difficult but important for prognosis. Tissue motion annular displacement tracks displacement of the tricuspid annulus toward the apex. We evaluated this measure alongside fractional area change (FAC) on patients with single, RV prior to the bidirectional Glenn procedure. We tested both measures for correlation with outcomes. Methods: Retrospective measurement of tissue motion annular displacement and FAC was performed on echocardiographic clips obtained prior to the bidirectional Glenn. A chart review included postoperative outcomes and midterm mortality/transplant. Bivariate correlations and Cox proportional hazards models were used for analyses. Results: Fifty-one patients with dominant RV underwent the bidirectional Glenn procedure and all had image quality that allowed analysis. The age ranged from 3 to 11 months (median 4 months). Neither tissue motion annular displacement nor FAC correlated with short-term postoperative outcomes. Tissue motion annular displacement was independently predictive of mortality/transplant ( P = .03) in the Cox hazard model. The mean for survivors was 12.4% and for nonsurvivors/transplants was 10.0%. Tissue motion annular displacement intra-observer variability was 2.8% (1.2%-3.5%). Interobserver mean variability was 6.1% (3.3%-8.1%). Fractional area change was not predictive of mortality/transplant. Conclusion: Tissue motion annular displacement is an independent predictor of midterm mortality/transplant after the bidirectional Glenn procedure in patients with single, RV, in this study. It may outperform FAC in this regard and has good reproducibility. Tissue motion annular displacement may be a useful measure in identifying high-risk children in this population.
Databáze:	MEDLINE
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