Contemporary Burn Survival.
| Autor: | Capek KD; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX., Sousse LE; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX., Hundeshagen G; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX., Voigt CD; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX., Suman OE; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX., Finnerty CC; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX; Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston, TX., Jennings K; Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX., Herndon DN; Department of Surgery, University of Texas Medical Branch, Galveston, TX; Shriners Hospitals for Children-Galveston, Galveston, TX; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX. Electronic address: dherndon@utmb.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the American College of Surgeons [J Am Coll Surg] 2018 Apr; Vol. 226 (4), pp. 453-463. Date of Electronic Publication: 2018 Mar 09. |
| DOI: | 10.1016/j.jamcollsurg.2017.12.045 |
| Abstrakt: | Background: The standard of burn treatment today reflects major advances. We sought to quantitate the impact of these advances on burn survival via age-stratified mortality ratios compared with other reported mortality analyses in burns. Study Design: Age, percent of the total body surface area (TBSA) burned, presence of inhalation injury, length of stay, and survival status were recorded at admission and at discharge for all new burn admissions between 1989 and 2017. The expected mortality probability was calculated using historical multiple regression techniques and compared with observed data. We developed a prediction model for our observed data. Results: Between 1989 and 2017, there were 10,384 consecutive new burn admissions, with 355 mortalities (median age, 13 years; median percent TBSA burn, 11%). We saw a significant decrease in our observed mortality data compared to historical predictions (p < 0.0001), and a 2% reduction per year in mortality during the 3 decades. The prediction model of mortality for the data is as follows: Pr(dying) = e x /(1 + e x ) where x = -6.44 - 0.12 age + 0.0042 age 2 - 0.0000283 age 3 + 0.0499 TBSA + 1.21 Inhalation Injury + 0.015 third degree TBSA. Conclusions: The reduction in mortality over time may be attributed to successful changes in standard of care protocols in the burn center that improved the outlook for burned individuals, including protocols for management of inhalation injury, nutrition, resuscitation, and early excision and grafting. (Copyright © 2018. Published by Elsevier Inc.) |
| Databáze: | MEDLINE |
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